5-Amino-1MQ 50mg

Our 5-Amino-1MQ 50mg vial holds 50mg of lyophilized 5-Amino-1MQ, an NNMT inhibitor. It’s intended for lab research only.

About 5-Amino-1MQ

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small molecule, not a peptide, that blocks the enzyme nicotinamide N-methyltransferase (NNMT). NNMT is especially active in fat tissue.

Because it’s small and membrane-permeable, it gets into fat cells easily, which makes it a useful tool for studying NNMT’s role in metabolism.

How 5-Amino-1MQ works

NNMT moves a methyl group onto nicotinamide, a form of vitamin B3. Fat cells make a lot of it. Blocking it leaves more nicotinamide available for NAD+ production and changes the cell’s methyl balance.

5-Amino-1MQ is a small, membrane-permeable NNMT inhibitor. In mouse fat cells it raised NAD+ and reduced fat storage, which is why it’s studied in obesity and aging models.

5-Amino-1MQ 50mg product details

• Compound: 5-Amino-1MQ
• Structure: quinolinium small molecule
• Amount: 50mg per vial
• Form: lyophilized (freeze-dried) powder
• Label: compound name and amount printed on every unit
• SKU: 5AM1-50
• Use: laboratory research only

5-Amino-1MQ research

Neelakantan and colleagues reported in Biochemical Pharmacology in 2018 that 5-Amino-1MQ reduced body weight and white fat mass in diet-induced obese mice, and shrank fat cells, without changing how much they ate.

Follow-up mouse work has looked at muscle aging and recovery. There are no published human trials.

To read the papers yourself, start with this PubMed search for 5-Amino-1MQ.

5-Amino-1MQ compared with similar compounds

Labs choosing 5-Amino-1MQ 50mg usually weigh it against a few close relatives. 5-Amino-1MQ is a small molecule that blocks the enzyme NNMT inside fat cells, while:

• AOD-9604 is hGH fragment 177-191 with an extra tyrosine, studied for fat breakdown without raising IGF-1
• MOTS-c is a 16-amino-acid peptide coded in mitochondrial DNA, studied for glucose use in muscle

These are all studied for fat metabolism but act in different places: AOD-9604 and Fragment 176-191 on fat tissue from outside, 5-Amino-1MQ and MOTS-c from inside the cell. See them all on our weight loss peptides page.

5-Amino-1MQ 50mg reconstitution and concentration

Concentration is the amount in the vial divided by the volume of water you add. With 50mg of powder in this vial:

• 2mL of bacteriostatic water gives 25mg/mL
• 3mL of bacteriostatic water gives 16.67mg/mL
• 5mL of bacteriostatic water gives 10mg/mL

Go with whichever number is easiest to work with in your protocol, and label the vial with the concentration and the date you mixed it.

Most labs use sterile bacteriostatic water. We stock bacteriostatic water in 3mL, 10mL and 30mL sizes. Warm the sealed vial to room temperature, add the water slowly along the glass wall and swirl gently until it’s clear. Never shake it.

Storing 5-Amino-1MQ 50mg

Store sealed vials of 5-Amino-1MQ 50mg in the freezer at -20°C, out of direct light. Mixed solution goes in the fridge at 2 to 8°C and should be used within about 28 days.

Running several vials at once? Our 10 vial kit case holds up to ten vials upright in separate wells under a clear lid, which keeps a fridge shelf tidy and the labels easy to read.

Checking your 5-Amino-1MQ 50mg

The vial label shows the compound and the amount. For anything your lab needs on file beyond that, email Peptira support with the product name before you place the order.

Labs that check material in-house normally confirm identity with mass spectrometry, which checks the molecular weight, and measure purity with HPLC, which separates the main compound from anything else in the sample.

If you run a long study, try to order everything you need at once and log it when it arrives. It removes one variable from your results.

Ordering 5-Amino-1MQ 50mg for a full study

Start from the protocol. Total the amount every arm needs from the first time point to the last, divide by the 50mg in a vial and add a spare. It’s cheaper to order once than to wait on a second shipment halfway through.

Only reconstitute what you’ll use in the next few weeks. Sealed vials stay stable in the freezer, while a mixed vial should be finished within about 28 days.

If you order more than one vial, check that the batch numbers match before you start. Running a whole study on one batch removes one variable.

Other weight loss peptides to look at

• Lipo-C XL 20mL, a ready-made liquid vial
• TIRZ-2 30mg, a GIP/GLP-1 agonist
• AICAR 50mg, an AMPK activator
• Peel’d 20mL, a ready-made liquid vial
• Lipo-C 10mL, a ready-made liquid vial

Browse the full weight loss peptides and NAD+ and mitochondrial peptides range, see every vial on our research peptides page or head back to the Peptira home page.

5-Amino-1MQ 50mg FAQ

How much is in the 5-Amino-1MQ 50mg vial?

50mg of freeze-dried powder. The amount is printed on the label.

What do I mix 5-Amino-1MQ 50mg with?

Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.

How should I store it?

Keep sealed vials in the freezer at -20°C. Once mixed, refrigerate at 2 to 8°C and use within about 28 days.

Can 5-Amino-1MQ be used in people or animals?

No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.

Is 5-Amino-1MQ 50mg in stock?

Yes. 5-Amino-1MQ 50mg is in stock and ready to ship.

Order 5-Amino-1MQ 50mg today

Ready to order? 5-Amino-1MQ 50mg costs $129.00 and is in stock. Use code PEPTIRA10 for 10% off, pay with crypto for a further discount, and shipping costs nothing wherever you are.

Need more for the same project? See the rest of our weight loss peptides and NAD+ and mitochondrial peptides, or go back to the Peptira home page.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.