AOD-9604 5mg

AOD-9604 5mg is a 5mg vial of AOD-9604, a modified hGH fragment, supplied as freeze-dried powder. It’s sold for laboratory research only.

About AOD-9604

AOD-9604 is a modified fragment of human growth hormone (residues 177-191 with an added tyrosine). It was developed at Monash University to study fat metabolism without GH’s effects on growth or IGF-1.

Metabolic Pharmaceuticals took it into trials.

AOD-9604 mechanism of action

Growth hormone has a region near its C-terminal end, residues 177 to 191, that seems to account for its effect on fat breakdown. AOD-9604 is that fragment with a tyrosine added at the front.

In animal studies it increased lipolysis and reduced lipogenesis in fat cells. It doesn’t bind the growth hormone receptor the way full GH does, and it didn’t raise IGF-1 in trials, which is what made it interesting as a tool for separating GH’s fat effects from its growth effects.

AOD-9604 5mg product details

• Compound: AOD-9604
• Also known as: hGH fragment 177-191
• CAS number: 221231-10-3
• Molecular formula: C78H123N23O23S2
• Molar mass: 1,815.1 g/mol
• Structure: hGH fragment 177-191 with an added N-terminal tyrosine
• Amount: 5mg per vial
• Form: lyophilized (freeze-dried) powder
• Label: compound name and amount printed on every unit
• SKU: AOD9604-5
• Use: laboratory research only

Published AOD-9604 studies

Heffernan and colleagues reported in 2001 that it reduced body fat in obese mice.

Phase 2b trials didn’t show significant weight loss compared with placebo.

To read the papers yourself, start with this PubMed search for AOD-9604.

How AOD-9604 compares

Labs choosing AOD-9604 5mg usually weigh it against a few close relatives. AOD-9604 is hGH fragment 177-191 with an extra tyrosine, studied for fat breakdown without raising IGF-1, while:

• 5-Amino-1MQ is a small molecule that blocks the enzyme NNMT inside fat cells
• MOTS-c is a 16-amino-acid peptide coded in mitochondrial DNA, studied for glucose use in muscle

These are all studied for fat metabolism but act in different places: AOD-9604 and Fragment 176-191 on fat tissue from outside, 5-Amino-1MQ and MOTS-c from inside the cell. See them all on our weight loss peptides page.

Reconstituting AOD-9604 5mg

The amount of liquid you add sets the concentration. For a vial holding 5mg:

• 1mL of bacteriostatic water gives 5mg/mL
• 2mL of bacteriostatic water gives 2.5mg/mL
• 3mL of bacteriostatic water gives 1.67mg/mL

Pick the volume that keeps your own calculations simple, then write the concentration and the mixing date on the label.

Most labs use sterile bacteriostatic water. We stock bacteriostatic water in 3mL, 10mL and 30mL sizes. Warm the sealed vial to room temperature, add the water slowly along the glass wall and swirl gently until it’s clear. Never shake it.

Storing AOD-9604 5mg

The dry powder keeps best cold and dark. A freezer at -20°C is right for long-term storage. After reconstitution, store it in the fridge at 2 to 8°C and finish it within roughly four weeks.

Running several vials at once? Our 10 vial kit case holds up to ten vials upright in separate wells under a clear lid, which keeps a fridge shelf tidy and the labels easy to read.

Checking your AOD-9604 5mg

Every AOD-9604 5mg vial carries a printed label with the compound name and amount, so you always know what you’re holding. If your lab needs batch paperwork for its records, contact Peptira support before you order and ask what’s available for the current batch.

Many labs run their own identity check when a new batch arrives. For peptides, purity is usually measured by HPLC, which separates a sample into its parts and reports the main compound as a share of the total. Mass spectrometry is often run alongside it to confirm the molecular weight.

Write the order date and the vial details into your lab notes. If a result looks odd later, you can tie it back to the exact material you used.

Planning a study with AOD-9604 5mg

Work out the total amount before you order. Add up what each arm of the study uses across every time point, then divide by 5mg. Round up by one vial so a spoiled sample or a repeat run doesn’t stall the project.

Mix one vial at a time and keep the rest sealed in the freezer. Dry powder keeps far longer than solution, so there’s no reason to reconstitute everything at the start.

If you order more than one vial, check that the batch numbers match before you start. Running a whole study on one batch removes one variable.

Other weight loss peptides to look at

• AICAR 50mg, an AMPK activator
• CAG-4 10mg, an amylin analog
• 5-Amino-1MQ 50mg, an NNMT inhibitor
• RETA-3 10mg, a triple agonist
• TIRZ-2 10mg, a GIP/GLP-1 agonist

Browse the full weight loss peptides range, see every vial on our research peptides page or head back to the Peptira home page.

AOD-9604 5mg questions

How much is in the AOD-9604 5mg vial?

5mg of freeze-dried powder. The amount is printed on the label.

How should I store it?

Keep sealed vials in the freezer at -20°C. Once mixed, refrigerate at 2 to 8°C and use within about 28 days.

Can AOD-9604 be used in people or animals?

No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.

Is AOD-9604 5mg in stock?

Yes. AOD-9604 5mg is in stock and ready to ship.

Where can I buy AOD-9604 5mg?

Right here at Peptira. Add AOD-9604 5mg to the cart on this page and it ships free worldwide.

Order AOD-9604 5mg today

Ready to order? AOD-9604 5mg costs $49.00 and is in stock. Use code PEPTIRA10 for 10% off, pay with crypto for a further discount, and shipping costs nothing wherever you are. Need water to mix it? Add bacteriostatic water to the same order.

Need more for the same project? See the rest of our weight loss peptides, or go back to the Peptira home page.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.