SS-31 10mg

Our SS-31 10mg vial holds 10mg of lyophilized SS-31, a mitochondria-targeted tetrapeptide. It’s sold for laboratory research only.

SS-31 at a glance

SS-31, also called elamipretide, is a four-amino-acid peptide: D-Arg-Dmt-Lys-Phe-NH2. It alternates positive charges with aromatic rings, a design that lets it slip through cell membranes and collect in mitochondria.

Once there, it binds cardiolipin, a fat that’s found almost only in the inner mitochondrial membrane and that holds the energy-making machinery in place.

How SS-31 acts in the lab

Cardiolipin holds together the protein complexes that make ATP in mitochondria. When it’s oxidized, those complexes work less well and leak more free radicals.

SS-31 binds cardiolipin and protects it, which in lab studies kept the electron transport chain working more efficiently and cut oxidative damage. It doesn’t depend on the membrane voltage to get into mitochondria, which sets it apart from other targeted antioxidants.

SS-31 10mg technical data

• Compound: SS-31
• CAS number: 736992-21-5
• Molecular formula: C32H49N9O5
• Molar mass: 639.8 g/mol
• Sequence: D-Arg-Dmt-Lys-Phe-NH2
• Amount: 10mg per vial
• Form: lyophilized (freeze-dried) powder
• Label: compound name and amount printed on every unit
• SKU: SS31-10
• Use: laboratory research only

SS-31 research

Hazel Szeto and Peter Schiller designed it in the early 2000s; SS stands for Szeto-Schiller. Stealth BioTherapeutics took it into clinical trials for mitochondrial diseases, including primary mitochondrial myopathy and Barth syndrome.

It’s one of the few mitochondria-targeted peptides with real human trial data. This vial is research material, not the clinical product.

The primary literature is on PubMed, run by the US National Library of Medicine. Here’s a search for SS-31 studies to start from.

Checking your SS-31 10mg

The vial label shows the compound and the amount. For anything your lab needs on file beyond that, email Peptira support with the product name before you place the order.

If you verify incoming material yourself, the standard methods are HPLC for purity and mass spectrometry for identity. HPLC splits the sample and reports the main peak as a percentage, while mass spec confirms that peak has the right molecular weight.

Keep a record of which vial went into which experiment. Matching results to material is the simplest way to rule it out when an experiment doesn’t behave.

How to reconstitute SS-31 10mg

The amount of liquid you add sets the concentration. For a vial holding 10mg:

• 1mL of bacteriostatic water gives 10mg/mL
• 2mL of bacteriostatic water gives 5mg/mL
• 3mL of bacteriostatic water gives 3.33mg/mL

Pick the volume that keeps your own calculations simple, then write the concentration and the mixing date on the label.

Use sterile bacteriostatic water, like our bacteriostatic water. Let the vial reach room temperature, run the water slowly down the inside of the glass, then roll the vial gently until the powder dissolves. Don’t shake it. Shaking can shear peptide chains.

SS-31 10mg storage and shelf life

Freeze-dried SS-31 10mg handles room temperature fine during shipping, but for anything longer keep it in a freezer at -20°C, away from light. Once mixed, keep it in the fridge at 2 to 8°C and use it within about four weeks.

Leave sealed vials sealed until you need them. Dry powder in a closed vial lasts far longer than solution, so there’s no reason to mix more than one at a time.

Other SS-31 strengths

• SS-31 10mg (this page): $49.00, about $4.90 per mg
• SS-31 50mg: $139.00, about $2.78 per mg

SS-31 10mg is the entry size, handy when you only need a little or want to try SS-31 before committing to a bigger vial.

Ordering SS-31 10mg for a full study

Work out the total amount before you order. Add up what each arm of the study uses across every time point, then divide by 10mg. Round up by one vial so a spoiled sample or a repeat run doesn’t stall the project.

Only reconstitute what you’ll use in the next few weeks. Sealed vials stay stable in the freezer, while a mixed vial should be finished within about 28 days.

If you order more than one vial, check that the batch numbers match before you start. Running a whole study on one batch removes one variable.

Related to SS-31 10mg

• AICAR 50mg, an AMPK activator
• BAM-15 Capsules 50mg, a capsule format
• NAD+ 1000mg, a coenzyme
• 5-Amino-1MQ 50mg, an NNMT inhibitor
• SLU-PP-332 BAM-15 Capsules, a capsule format

Browse the full NAD+ and mitochondrial peptides and anti-aging peptides range, see every vial on our research peptides page or head back to the Peptira home page.

SS-31 10mg FAQ

How much is in the SS-31 10mg vial?

10mg of freeze-dried powder. The amount is printed on the label.

Is SS-31 10mg in stock?

Yes. SS-31 10mg is in stock and ready to ship.

Where can I buy SS-31 10mg?

Right here at Peptira. Add this vial to the cart on this page and it ships free worldwide.

What do I mix SS-31 10mg with?

Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.

How should I store it?

Keep sealed vials in the freezer at -20°C. Once mixed, refrigerate at 2 to 8°C and use within about 28 days.

Buy SS-31 10mg from Peptira

Ready to order? This vial costs $49.00 and is in stock. Use code PEPTIRA10 for 10% off, pay with crypto for a further discount, and shipping costs nothing wherever you are.

Need more for the same project? See the rest of our NAD+ and mitochondrial peptides and anti-aging peptides, or go back to the Peptira home page.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.