TB-500 10mg

TB-500 10mg is a 10mg vial of TB-500, a 43-amino-acid actin-binding protein, supplied as freeze-dried powder. It’s for in-vitro and lab research only.

TB-500 is the name most research catalogs use for thymosin beta-4.

TB-500 (thymosin beta-4) at a glance

TB-500 here means thymosin beta-4, a 43-amino-acid protein found in nearly every cell in the body, with high levels in platelets and white blood cells. Inside the cell it binds actin, the protein cells use to change shape and move.

The TB-500 we sell is the full-length 43-residue sequence, acetylated at the N-terminus like the natural protein. It isn’t an approved medicine, and it’s on the WADA prohibited list.

How TB-500 works

Thymosin beta-4’s main job is holding on to G-actin, the single building blocks of the cell’s internal scaffolding. By controlling how much actin is free to polymerize, it controls how cells move and change shape.

Cell movement is the first step in repair, which is the link to the wound healing and blood vessel studies. The actin-binding work is done by a short stretch of the chain, LKKTETQ, at positions 17 to 23.

TB-500 10mg product details

• Compound: TB-500 (thymosin beta-4)
• Also known as: thymosin beta-4, Tβ4
• CAS number: 77591-33-4
• Molecular formula: C212H350N56O78S
• Molar mass: 4,963.4 g/mol
• Structure: 43 amino acids (thymosin beta-4)
• Amount: 10mg per vial
• Form: lyophilized (freeze-dried) powder
• Label: compound name and amount printed on every unit
• SKU: TB500-10
• Use: laboratory research only

TB-500 research

Goldstein and colleagues reviewed thymosin beta-4’s role in wound repair in 2012, covering faster closure of skin wounds and new blood vessel growth in animal models.

Bock-Marquette and colleagues reported in Nature (2004) that thymosin beta-4 improved heart cell survival after injury in mice.

To read the papers yourself, start with this PubMed search for TB-500.

How TB-500 compares

Here’s how TB-500 10mg fits among related compounds. TB-500 is the 43-amino-acid actin-binding protein, studied for cell movement and wound repair. By comparison:

• BPC-157 is the 15-amino-acid repair peptide with the largest body of rodent research
• KPV is a three-amino-acid alpha-MSH fragment studied for calming inflammation
• ARA-290 is an 11-amino-acid peptide from erythropoietin that protects tissue without raising red cells
• GHK-Cu is the copper-binding tripeptide studied for collagen and skin repair

These are the main peptides in repair research. Each covers a different step, from blood vessel growth and cell movement to calming inflammation and rebuilding the skin matrix. See them all on our healing and recovery peptides page.

TB-500 in other formats

TB-500 also comes in these products, in case a different format suits your study better:

• Wolverine Blend 10mg (TB-500, BPC-157) (blend vial, $79.00)
• Phoenix Blend 30mg (KPV, TB-500, BPC-157) (blend vial, $119.00)
• GLOW Blend 70mg (GHK-Cu, BPC-157, TB-500) (blend vial, $149.00)
• KLOW Blend 80mg (GHK-Cu, BPC-157, TB-500, KPV) (blend vial, $149.00)

Checking your TB-500 10mg

Peptira labels each TB-500 10mg vial with the compound and the amount. Labs that file batch documentation should ask our support team about the current batch before ordering.

If you verify incoming material yourself, the standard methods are HPLC for purity and mass spectrometry for identity. HPLC splits the sample and reports the main peak as a percentage, while mass spec confirms that peak has the right molecular weight.

If you run a long study, try to order everything you need at once and log it when it arrives. It removes one variable from your results.

How to reconstitute TB-500 10mg

The amount of liquid you add sets the concentration. For a vial holding 10mg:

• 1mL of bacteriostatic water gives 10mg/mL
• 2mL of bacteriostatic water gives 5mg/mL
• 3mL of bacteriostatic water gives 3.33mg/mL

Go with whichever number is easiest to work with in your protocol, and label the vial with the concentration and the date you mixed it.

Use sterile bacteriostatic water, like our bacteriostatic water. Let the vial reach room temperature, run the water slowly down the inside of the glass, then roll the vial gently until the powder dissolves. Don’t shake it. Shaking can shear peptide chains.

How to store TB-500 10mg

Store sealed vials of TB-500 10mg in the freezer at -20°C, out of direct light. Mixed solution goes in the fridge at 2 to 8°C and should be used within about 28 days.

Running several vials at once? Our 10 vial kit case holds up to ten vials upright in separate wells under a clear lid, which keeps a fridge shelf tidy and the labels easy to read.

Related to TB-500 10mg

• KPV 10mg, an alpha-MSH tripeptide
• IGF-1 LR3 1mg, an IGF-1 analog
• Wolverine Blend 10mg (TB-500, BPC-157), TB-500 and BPC-157 in one vial
• BPC-157 10mg, a 15-amino-acid peptide
• GHK-Cu 100mg, a copper peptide

Browse the full healing and recovery peptides range, see every vial on our research peptides page or head back to the Peptira home page.

TB-500 10mg questions

How much is in the TB-500 10mg vial?

10mg of freeze-dried powder. The amount is printed on the label.

Where can I buy TB-500 10mg?

Right here at Peptira. Add TB-500 10mg to the cart on this page and it ships free worldwide.

What do I mix TB-500 10mg with?

Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.

How should I store it?

Keep sealed vials in the freezer at -20°C. Once mixed, refrigerate at 2 to 8°C and use within about 28 days.

Can TB-500 be used in people or animals?

No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.

Buy TB-500 10mg from Peptira

Ready to order? TB-500 10mg costs $49.00 and is in stock. Use code PEPTIRA10 for 10% off, pay with crypto for a further discount, and shipping costs nothing wherever you are. Need water to mix it? Add bacteriostatic water to the same order.

Need more for the same project? See the rest of our healing and recovery peptides, or go back to the Peptira home page.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.