KPV 10mg

KPV 10mg from Peptira is 10mg of KPV in a sealed glass vial. KPV is an alpha-MSH derived tripeptide. It’s sold for laboratory research only.

KPV at a glance

KPV is the tripeptide lysine-proline-valine, the C-terminal end of alpha-melanocyte stimulating hormone. It keeps alpha-MSH’s anti-inflammatory activity without the pigment effects.

It’s small enough to be taken up by gut cells through the PepT1 transporter, which is why it’s studied in models of gut inflammation.

How KPV acts in the lab

Alpha-MSH calms inflammation through melanocortin receptors. KPV is its last three amino acids and keeps much of that anti-inflammatory activity.

Inside cells it lowers NF-kappaB signaling, the switch for many inflammatory genes. Gut cells take it up through the PepT1 transporter, which is why colitis models are where most of the work is.

KPV 10mg specifications

• Compound: KPV
• Also known as: Lys-Pro-Val
• CAS number: 67727-97-3
• Molecular formula: C16H30N4O4
• Molar mass: 342.4 g/mol
• Structure: Lys-Pro-Val
• Amount: 10mg per vial
• Form: lyophilized (freeze-dried) powder
• Label: compound name and amount printed on every unit
• SKU: KPV-10
• Use: laboratory research only

What the research says about KPV

Dalmasso and colleagues reported in Gastroenterology (2008) that KPV reduced inflammation in mouse colitis models and was taken up through PepT1.

Laroui and colleagues later packaged KPV in nanoparticles and saw similar effects in mice.

The primary literature is on PubMed, run by the US National Library of Medicine. Here’s a search for KPV studies to start from.

How KPV compares

Here’s how KPV 10mg fits among related compounds. KPV is a three-amino-acid alpha-MSH fragment studied for calming inflammation. By comparison:

• BPC-157 is the 15-amino-acid repair peptide with the largest body of rodent research
• TB-500 is the 43-amino-acid actin-binding protein, studied for cell movement and wound repair
• ARA-290 is an 11-amino-acid peptide from erythropoietin that protects tissue without raising red cells
• GHK-Cu is the copper-binding tripeptide studied for collagen and skin repair

These are the main peptides in repair research. Each covers a different step, from blood vessel growth and cell movement to calming inflammation and rebuilding the skin matrix. See them all on our healing and recovery peptides page.

Other ways to buy KPV

KPV also comes in these products, in case a different format suits your study better:

• Phoenix Blend 30mg (KPV, TB-500, BPC-157) (blend vial, $119.00)
• KLOW Blend 80mg (GHK-Cu, BPC-157, TB-500, KPV) (blend vial, $149.00)

KPV 10mg quality and handling

Every KPV 10mg vial carries a printed label with the compound name and amount, so you always know what you’re holding. If your lab needs batch paperwork for its records, contact Peptira support before you order and ask what’s available for the current batch.

If you verify incoming material yourself, the standard methods are HPLC for purity and mass spectrometry for identity. HPLC splits the sample and reports the main peak as a percentage, while mass spec confirms that peak has the right molecular weight.

If you run a long study, try to order everything you need at once and log it when it arrives. It removes one variable from your results.

How to reconstitute KPV 10mg

Concentration is the amount in the vial divided by the volume of water you add. With 10mg of powder in this vial:

• 1mL of bacteriostatic water gives 10mg/mL
• 2mL of bacteriostatic water gives 5mg/mL
• 3mL of bacteriostatic water gives 3.33mg/mL

Go with whichever number is easiest to work with in your protocol, and label the vial with the concentration and the date you mixed it.

Bacteriostatic water is the usual choice, and acetic acid helps with peptides that won’t dissolve in water alone. Add it slowly so it runs down the side of the vial, then swirl or roll until everything dissolves. Shaking can shear peptide chains. Skip it.

How to store KPV 10mg

Store sealed vials of KPV 10mg in the freezer at -20°C, out of direct light. Mixed solution goes in the fridge at 2 to 8°C and should be used within about 28 days.

Running several vials at once? Our 10 vial kit case holds up to ten vials upright in separate wells under a clear lid, which keeps a fridge shelf tidy and the labels easy to read.

Other healing and recovery peptides to look at

• LL-37 5mg, an antimicrobial peptide
• Phoenix Blend 30mg (KPV, TB-500, BPC-157), KPV, TB-500 and BPC-157 in one vial
• GHK-Cu 50mg, a copper peptide
• KLOW Blend 80mg (GHK-Cu, BPC-157, TB-500, KPV), GHK-Cu, BPC-157, TB-500 and KPV in one vial
• ARA-290 10mg, an EPO-derived peptide

Browse the full healing and recovery peptides and immune peptides range, see every vial on our research peptides page or head back to the Peptira home page.

KPV 10mg questions

How much is in the KPV 10mg vial?

10mg of freeze-dried powder. The amount is printed on the label.

Where can I buy KPV 10mg?

Right here at Peptira. Add KPV 10mg to the cart on this page and it ships free worldwide.

What do I mix KPV 10mg with?

Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.

How should I store it?

Keep sealed vials in the freezer at -20°C. Once mixed, refrigerate at 2 to 8°C and use within about 28 days.

Can KPV be used in people or animals?

No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.

Order KPV 10mg today

Ready to order? KPV 10mg costs $49.00 and is in stock. Use code PEPTIRA10 for 10% off, pay with crypto for a further discount, and shipping costs nothing wherever you are.

Need more for the same project? See the rest of our healing and recovery peptides and immune peptides, or go back to the Peptira home page.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.