CJC-1295 DAC 5mg

CJC-1295 DAC 5mg is a 5mg vial of CJC-1295 DAC, a long-acting GHRH analog, supplied as freeze-dried powder. It’s for in-vitro and lab research only.

This is the long-acting version with the drug affinity complex. If you want the short-acting form, see CJC-1295 No DAC 10mg.

CJC-1295 with DAC at a glance

CJC-1295 with DAC is modified GRF(1-29), the first 29 amino acids of growth hormone releasing hormone with four substitutions, plus a lysine carrying a maleimide linker. That linker is the drug affinity complex, made by ConjuChem in Montreal.

Once in the blood, the DAC bonds to albumin. That takes the half-life from minutes to about a week, which is the whole difference between this peptide and CJC-1295 no DAC.

CJC-1295 DAC mechanism of action

The peptide part works like GHRH. It binds the GHRH receptor on pituitary somatotroph cells and switches on the cAMP pathway that drives GH release and GH gene expression.

The DAC linker reacts with a free cysteine on albumin, so the peptide rides around on a protein that lasts weeks. That gives a steady, long GHRH signal instead of the short burst you get from sermorelin or CJC-1295 no DAC.

CJC-1295 DAC 5mg technical data

• Compound: CJC-1295 with DAC
• Also known as: CJC-1295 with drug affinity complex
• CAS number: 863288-34-0
• Molecular formula: C165H269N47O46
• Molar mass: 3,647.2 g/mol
• Structure: modified GRF(1-29) with Lys(maleimidopropionyl)-NH2
• Amount: 5mg per vial
• Form: lyophilized (freeze-dried) powder
• Label: compound name and amount printed on every unit
• SKU: CJCD-5
• Use: laboratory research only

CJC-1295 DAC research

Teichman and colleagues reported in the Journal of Clinical Endocrinology and Metabolism in 2006 that single injections in healthy adults raised GH for about six days and IGF-1 for up to two weeks.

A follow-up paper by Ionescu and Frohman found that GH stayed pulsatile on CJC-1295, with higher baseline levels between pulses. Development stopped after phase 2.

To read the papers yourself, start with this PubMed search for CJC-1295 DAC.

How CJC-1295 DAC compares

Labs choosing CJC-1295 DAC 5mg usually weigh it against a few close relatives. CJC-1295 DAC binds albumin and lasts about a week, giving a raised GH baseline instead of short pulses, while:

• CJC-1295 No DAC is a stabilized GHRH(1-29) with a half-life of about 30 minutes, giving short, natural-looking pulses
• Sermorelin is the unmodified first 29 amino acids of GHRH, broken down within minutes
• Tesamorelin is full-length GHRH with a fatty acid cap, the only GHRH analog currently approved as a drug in the US
• Ipamorelin is the most selective ghrelin-receptor peptide, with little effect on cortisol or prolactin
• GHRP-6 releases GH and strongly raises appetite, the classic tool for feeding research

The GHRH analogs (CJC-1295, sermorelin, tesamorelin) all act on the same receptor, and the real difference is how long each one lasts. Ipamorelin, GHRP-2 and GHRP-6 work on the ghrelin receptor instead, which is why labs so often pair one from each side. See them all on our growth hormone peptides page.

Reconstituting CJC-1295 DAC 5mg

Concentration is the amount in the vial divided by the volume of water you add. With 5mg of powder in this vial:

• 1mL of bacteriostatic water gives 5mg/mL
• 2mL of bacteriostatic water gives 2.5mg/mL
• 3mL of bacteriostatic water gives 1.67mg/mL

Choose the volume that suits your measurements. Mark the vial with the concentration and date so nobody has to guess later.

Most labs use sterile bacteriostatic water. We stock bacteriostatic water in 3mL, 10mL and 30mL sizes. Warm the sealed vial to room temperature, add the water slowly along the glass wall and swirl gently until it’s clear. Never shake it.

How to store CJC-1295 DAC 5mg

The dry powder keeps best cold and dark. A freezer at -20°C is right for long-term storage. After reconstitution, store it in the fridge at 2 to 8°C and finish it within roughly four weeks.

Let a frozen vial warm up to room temperature before you open it. Cold glass pulls moisture out of the air, and moisture is what degrades dry peptide.

Checking your CJC-1295 DAC 5mg

Peptira labels each CJC-1295 DAC 5mg vial with the compound and the amount. Labs that file batch documentation should ask our support team about the current batch before ordering.

If you verify incoming material yourself, the standard methods are HPLC for purity and mass spectrometry for identity. HPLC splits the sample and reports the main peak as a percentage, while mass spec confirms that peak has the right molecular weight.

If you run a long study, try to order everything you need at once and log it when it arrives. It removes one variable from your results.

Other growth hormone peptides to look at

• IGF-1 LR3 1mg, an IGF-1 analog
• Tesamorelin 10mg, a GHRH analog
• CJC-1295 No DAC 10mg, a GHRH analog
• GHRP-6 5mg, a GH releasing peptide
• Ipamorelin CJC-1295 Blend 10mg, Ipamorelin and CJC-1295 No DAC in one vial

Browse the full growth hormone peptides range, see every vial on our research peptides page or head back to the Peptira home page.

CJC-1295 DAC 5mg FAQ

How much is in the CJC-1295 DAC 5mg vial?

5mg of freeze-dried powder. The amount is printed on the label.

Where can I buy CJC-1295 DAC 5mg?

Right here at Peptira. Add CJC-1295 DAC 5mg to the cart on this page and it ships free worldwide.

What do I mix CJC-1295 DAC 5mg with?

Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.

How should I store it?

Keep sealed vials in the freezer at -20°C. Once mixed, refrigerate at 2 to 8°C and use within about 28 days.

Can CJC-1295 DAC be used in people or animals?

No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.

Buy CJC-1295 DAC 5mg from Peptira

Order CJC-1295 DAC 5mg now for $39.00. It’s in stock, code PEPTIRA10 takes 10% off at checkout, and we ship free to the US, Canada, Europe and Australia. Choose crypto at checkout for an extra discount.

Need more for the same project? See the rest of our growth hormone peptides, or go back to the Peptira home page.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.