PT-141 10mg

Our PT-141 10mg vial holds 10mg of lyophilized PT-141, a melanocortin receptor agonist. It’s intended for lab research only.

About PT-141

PT-141, also called bremelanotide, is a cyclic seven-amino-acid peptide developed from Melanotan II. It activates melanocortin receptors in the brain, mainly MC4R.

Palatin Technologies developed it, and the FDA approved it in 2019 as Vyleesi for hypoactive sexual desire disorder in premenopausal women.

How PT-141 works

PT-141 activates MC4R and MC3R in the hypothalamus, receptors involved in sexual motivation and arousal pathways. It acts on the brain, not on blood flow, which sets it apart from PDE5 inhibitors.

Chemically it’s Melanotan 2 with a free acid where Melanotan 2 has a C-terminal amide.

PT-141 10mg product details

• Compound: PT-141
• Also known as: bremelanotide
• CAS number: 189691-06-3
• Molecular formula: C50H68N14O10
• Molar mass: 1,025.2 g/mol
• Structure: cyclic heptapeptide
• Amount: 10mg per vial
• Form: lyophilized (freeze-dried) powder
• Label: compound name and amount printed on every unit
• SKU: PT141-10
• Use: laboratory research only

What the research says about PT-141

The two RECONNECT phase 3 trials, published in Obstetrics & Gynecology in 2019, were the basis for that approval.

Earlier work traced its effect to the central nervous system. PDE5 inhibitors, by contrast, work on blood flow.

For the original studies, try this PubMed search from the National Library of Medicine.

PT-141 compared with similar compounds

Labs choosing PT-141 10mg usually weigh it against a few close relatives. PT-141 is a melanocortin agonist derived from Melanotan II, acting on MC4 receptors in the brain, while:

• Kisspeptin sits at the top of the reproductive axis and triggers GnRH release
• Oxytocin is the nine-amino-acid hormone behind labor, milk release and social bonding

These three act on separate hormone systems in the brain: melanocortin receptors, the kisspeptin receptor that controls GnRH, and the oxytocin receptor. See them all on our hormone peptides page.

PT-141 10mg quality and handling

Every PT-141 10mg vial carries a printed label with the compound name and amount, so you always know what you’re holding. If your lab needs batch paperwork for its records, contact Peptira support before you order and ask what’s available for the current batch.

Many labs run their own identity check when a new batch arrives. For peptides, purity is usually measured by HPLC, which separates a sample into its parts and reports the main compound as a share of the total. Mass spectrometry is often run alongside it to confirm the molecular weight.

If you run a long study, try to order everything you need at once and log it when it arrives. It removes one variable from your results.

Reconstituting PT-141 10mg

Concentration is the amount in the vial divided by the volume of water you add. With 10mg of powder in this vial:

• 1mL of bacteriostatic water gives 10mg/mL
• 2mL of bacteriostatic water gives 5mg/mL
• 3mL of bacteriostatic water gives 3.33mg/mL

Pick the volume that keeps your own calculations simple, then write the concentration and the mixing date on the label.

Bacteriostatic water is the usual choice, and acetic acid helps with peptides that won’t dissolve in water alone. Add it slowly so it runs down the side of the vial, then swirl or roll until everything dissolves. Shaking can shear peptide chains. Skip it.

How to store PT-141 10mg

The dry powder keeps best cold and dark. A freezer at -20°C is right for long-term storage. After reconstitution, store it in the fridge at 2 to 8°C and finish it within roughly four weeks.

Let a frozen vial warm up to room temperature before you open it. Cold glass pulls moisture out of the air, and moisture is what degrades dry peptide.

Planning a study with PT-141 10mg

Start from the protocol. Total the amount every arm needs from the first time point to the last, divide by the 10mg in a vial and add a spare. It’s cheaper to order once than to wait on a second shipment halfway through.

Only reconstitute what you’ll use in the next few weeks. Sealed vials stay stable in the freezer, while a mixed vial should be finished within about 28 days.

Keep vials from one batch together in a study where you can. The batch number on the label ties each result back to the lab paperwork.

Related to PT-141 10mg

• Kisspeptin 10mg, a neuropeptide
• Oxytocin 2mg, a neuropeptide hormone
• FOXO4-DRI 10mg, a senolytic peptide
• Sermorelin 10mg, a GHRH analog
• AOD-9604 5mg, an hGH fragment

Browse the full hormone peptides range, see every vial on our research peptides page or head back to the Peptira home page.

PT-141 10mg questions

How much is in the PT-141 10mg vial?

10mg of freeze-dried powder. The amount is printed on the label.

Is PT-141 10mg in stock?

Yes. PT-141 10mg is in stock and ready to ship.

Where can I buy PT-141 10mg?

Right here at Peptira. Add PT-141 10mg to the cart on this page and it ships free worldwide.

What do I mix PT-141 10mg with?

Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.

How should I store it?

Keep sealed vials in the freezer at -20°C. Once mixed, refrigerate at 2 to 8°C and use within about 28 days.

Order PT-141 10mg today

Order this vial now for $49.00. It’s in stock, code PEPTIRA10 takes 10% off at checkout, and we ship free to the US, Canada, Europe and Australia. Choose crypto at checkout for an extra discount.

Need more for the same project? See the rest of our hormone peptides, or go back to the Peptira home page.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.