Epitalon 10mg

Our Epitalon 10mg vial holds 10mg of lyophilized Epithalon, a synthetic tetrapeptide. It’s intended for lab research only.

Epithalon at a glance

Epithalon (also spelled Epitalon) is the synthetic tetrapeptide Ala-Glu-Asp-Gly. Vladimir Khavinson’s group in St. Petersburg designed it from the amino acid makeup of epithalamin, an extract of the pineal gland.

It’s the best known of the Khavinson bioregulator peptides and is studied mainly for telomere biology and aging.

Epithalon mechanism of action

Epitalon is modeled on epithalamin, a peptide extract of the pineal gland. The pineal gland produces melatonin, and the original work looked at how it changed with age.

In cell culture, Khavinson’s group reported that epitalon switched on telomerase, the enzyme that rebuilds the protective caps on chromosome ends. Its other reported effects include normalizing melatonin rhythms in older animals.

Epitalon 10mg specifications

• Compound: Epithalon
• Also known as: Epitalon, AEDG
• CAS number: 307297-39-8
• Molecular formula: C14H22N4O9
• Molar mass: 390.3 g/mol
• Sequence: Ala-Glu-Asp-Gly
• Amount: 10mg per vial
• Form: lyophilized (freeze-dried) powder
• Label: compound name and amount printed on every unit
• SKU: EPIT-10
• Use: laboratory research only

What the research says about Epithalon

Khavinson and colleagues reported in 2003 that Epithalon switched on telomerase and lengthened telomeres in cultured human fibroblasts.

Studies from the same institute reported longer lifespans and fewer tumors in some strains of mice and rats. Most of this work comes from one group, so independent replication is still limited.

To read the papers yourself, start with this PubMed search for Epithalon.

Epitalon 10mg vs related compounds

Labs choosing Epitalon 10mg usually weigh it against a few close relatives. Epithalon is the tetrapeptide Ala-Glu-Asp-Gly, studied for telomerase activity, while:

• NAD+ is the coenzyme behind cell energy and sirtuin activity, whose levels fall with age
• Glutathione is the cell’s main antioxidant tripeptide
• MOTS-c is a 16-amino-acid peptide coded in mitochondrial DNA, studied for glucose use in muscle
• FOXO4-DRI is a D-amino-acid peptide built to push senescent cells into apoptosis

Aging research splits into a few processes, and each of these compounds targets one: telomeres, cell energy, oxidative stress, mitochondrial signaling or senescent cells. See them all on our anti-aging peptides page.

Reconstituting Epitalon 10mg

The amount of liquid you add sets the concentration. For a vial holding 10mg:

• 1mL of bacteriostatic water gives 10mg/mL
• 2mL of bacteriostatic water gives 5mg/mL
• 3mL of bacteriostatic water gives 3.33mg/mL

Choose the volume that suits your measurements. Mark the vial with the concentration and date so nobody has to guess later.

Bacteriostatic water is the usual choice, and acetic acid helps with peptides that won’t dissolve in water alone. Add it slowly so it runs down the side of the vial, then swirl or roll until everything dissolves. Shaking can shear peptide chains. Skip it.

How to store Epitalon 10mg

Store sealed vials of Epitalon 10mg in the freezer at -20°C, out of direct light. Mixed solution goes in the fridge at 2 to 8°C and should be used within about 28 days.

Running several vials at once? Our 10 vial kit case holds up to ten vials upright in separate wells under a clear lid, which keeps a fridge shelf tidy and the labels easy to read.

Epitalon 10mg quality notes

Every Epitalon 10mg vial carries a printed label with the compound name and amount, so you always know what you’re holding. If your lab needs batch paperwork for its records, contact Peptira support before you order and ask what’s available for the current batch.

If you verify incoming material yourself, the standard methods are HPLC for purity and mass spectrometry for identity. HPLC splits the sample and reports the main peak as a percentage, while mass spec confirms that peak has the right molecular weight.

Write the order date and the vial details into your lab notes. If a result looks odd later, you can tie it back to the exact material you used.

Ordering Epitalon 10mg for a full study

Work out the total amount before you order. Add up what each arm of the study uses across every time point, then divide by 10mg. Round up by one vial so a spoiled sample or a repeat run doesn’t stall the project.

Only reconstitute what you’ll use in the next few weeks. Sealed vials stay stable in the freezer, while a mixed vial should be finished within about 28 days.

If you order more than one vial, check that the batch numbers match before you start. Running a whole study on one batch removes one variable.

Often ordered with Epitalon 10mg

• Cartalax 20mg, a bioregulator tripeptide
• MOTS-c 10mg, a mitochondrial peptide
• NAD+ 500mg, a coenzyme
• FOXO4-DRI 10mg, a senolytic peptide
• Glutathione 1500mg, an antioxidant tripeptide

Browse the full anti-aging peptides range, see every vial on our research peptides page or head back to the Peptira home page.

Epitalon 10mg questions

How much is in the Epitalon 10mg vial?

10mg of freeze-dried powder. The amount is printed on the label.

Is Epitalon 10mg in stock?

Yes. Epitalon 10mg is in stock and ready to ship.

Where can I buy Epitalon 10mg?

Right here at Peptira. Add this vial to the cart on this page and it ships free worldwide.

What do I mix Epitalon 10mg with?

Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.

How should I store it?

Keep sealed vials in the freezer at -20°C. Once mixed, refrigerate at 2 to 8°C and use within about 28 days.

Buy Epitalon 10mg online

This vial is in stock at $49.00. Add it to the cart, enter code PEPTIRA10 at checkout for 10% off, and shipping is free worldwide. Paying with crypto at checkout takes a little more off. Need water to mix it? Add bacteriostatic water to the same order.

Need more for the same project? See the rest of our anti-aging peptides, or go back to the Peptira home page.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.