Melanotan 1 10mg

Melanotan 1 10mg is a 10mg vial of Melanotan 1, an alpha-MSH analog, supplied as freeze-dried powder. It’s intended for lab research only.

What is Melanotan 1 (afamelanotide)?

Melanotan I (afamelanotide) is a synthetic analog of alpha-MSH with two amino acid changes that make it more stable. It stimulates melanin production.

An implant form, Scenesse, is approved for erythropoietic protoporphyria.

How Melanotan 1 acts in the lab

Melanotan 1 acts on MC1R, the melanocortin receptor on pigment cells. Activating MC1R switches melanocytes from making pale pheomelanin to darker eumelanin.

Two swaps in the alpha-MSH sequence (norleucine at position 4 and D-phenylalanine at position 7) make it far more potent and longer lasting than the natural hormone. It’s more selective for MC1R than Melanotan 2.

Melanotan 1 10mg specifications

• Compound: Melanotan 1 (afamelanotide)
• CAS number: 75921-69-6
• Molecular formula: C78H111N21O19
• Molar mass: 1,646.9 g/mol
• Structure: 13 amino acids (Nle4, D-Phe7 alpha-MSH)
• Amount: 10mg per vial
• Form: lyophilized (freeze-dried) powder
• Label: compound name and amount printed on every unit
• SKU: MT1-10
• Use: laboratory research only

What the research says about Melanotan 1

Langendonk and colleagues published the phase 3 trials in the New England Journal of Medicine in 2015.

It was first developed at the University of Arizona in the 1980s.

To read the papers yourself, start with this PubMed search for Melanotan I.

Melanotan 1 10mg vs related compounds

Labs choosing Melanotan 1 10mg usually weigh it against a few close relatives. Melanotan 1 is the linear alpha-MSH analog, approved in Europe as afamelanotide for a light-sensitivity disorder, while:

• GHK-Cu is the copper-binding tripeptide studied for collagen and skin repair
• Melanotan 2 is a cyclic alpha-MSH analog that drives melanin production
• Glutathione is the cell’s main antioxidant tripeptide

These cover the main lines of skin research: the copper peptide GHK-Cu for repair and collagen, glutathione for oxidative stress and the melanocortin peptides for pigmentation. See them all on our skin and tanning peptides page.

Melanotan 1 10mg quality notes

Every Melanotan 1 10mg vial carries a printed label with the compound name and amount, so you always know what you’re holding. If your lab needs batch paperwork for its records, contact Peptira support before you order and ask what’s available for the current batch.

If you verify incoming material yourself, the standard methods are HPLC for purity and mass spectrometry for identity. HPLC splits the sample and reports the main peak as a percentage, while mass spec confirms that peak has the right molecular weight.

Keep a record of which vial went into which experiment. Matching results to material is the simplest way to rule it out when an experiment doesn’t behave.

Melanotan 1 10mg reconstitution and concentration

Concentration is the amount in the vial divided by the volume of water you add. With 10mg of powder in this vial:

• 1mL of bacteriostatic water gives 10mg/mL
• 2mL of bacteriostatic water gives 5mg/mL
• 3mL of bacteriostatic water gives 3.33mg/mL

Choose the volume that suits your measurements. Mark the vial with the concentration and date so nobody has to guess later.

Bacteriostatic water is the usual choice, and acetic acid helps with peptides that won’t dissolve in water alone. Add it slowly so it runs down the side of the vial, then swirl or roll until everything dissolves. Shaking can shear peptide chains. Skip it.

Storing Melanotan 1 10mg

Store sealed vials of Melanotan 1 10mg in the freezer at -20°C, out of direct light. Mixed solution goes in the fridge at 2 to 8°C and should be used within about 28 days.

Leave sealed vials sealed until you need them. Dry powder in a closed vial lasts far longer than solution, so there’s no reason to mix more than one at a time.

Planning a study with Melanotan 1 10mg

Work out the total amount before you order. Add up what each arm of the study uses across every time point, then divide by 10mg. Round up by one vial so a spoiled sample or a repeat run doesn’t stall the project.

Mix one vial at a time and keep the rest sealed in the freezer. Dry powder keeps far longer than solution, so there’s no reason to reconstitute everything at the start.

If you order more than one vial, check that the batch numbers match before you start. Running a whole study on one batch removes one variable.

Often ordered with Melanotan 1 10mg

• Glutathione 1500mg, an antioxidant tripeptide
• GLOW Blend 70mg (GHK-Cu, BPC-157, TB-500), GHK-Cu, BPC-157 and TB-500 in one vial
• GHK-Cu Capsules 2mg, a capsule format
• KLOW Blend 80mg (GHK-Cu, BPC-157, TB-500, KPV), GHK-Cu, BPC-157, TB-500 and KPV in one vial
• GHK-Cu Raw Powder, raw powder for formulation work

Browse the full skin and tanning peptides range, see every vial on our research peptides page or head back to the Peptira home page.

Common questions about Melanotan 1 10mg

How much is in the Melanotan 1 10mg vial?

10mg of freeze-dried powder. The amount is printed on the label.

Is Melanotan 1 10mg in stock?

Yes. Melanotan 1 10mg is in stock and ready to ship.

Where can I buy Melanotan 1 10mg?

Right here at Peptira. Add this vial to the cart on this page and it ships free worldwide.

What do I mix Melanotan 1 10mg with?

Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.

How should I store it?

Keep sealed vials in the freezer at -20°C. Once mixed, refrigerate at 2 to 8°C and use within about 28 days.

Buy Melanotan 1 10mg from Peptira

Ready to order? This vial costs $39.00 and is in stock. Use code PEPTIRA10 for 10% off, pay with crypto for a further discount, and shipping costs nothing wherever you are. Need water to mix it? Add bacteriostatic water to the same order.

Need more for the same project? See the rest of our skin and tanning peptides, or go back to the Peptira home page.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.